DoCM - Database of Curated Mutations

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Variant Data

Location

HGVS: ENST00000311189:c.182A>G
Reference Version: GRCh37
Chromosome: 11
Start: 533874
Stop: 533874
Strand: -1
Transcript: ENST00000311189 (ensembl - 74_37)
Gene: HRAS ( View drug interactions on DGIdb )

Information

Reference: T
Variant: C
Amino Acid: p.Q61R
Mutation Type: missense
Variant Type: SNV (SO:0001483)
cDNA Change: c.182
Tags: pathogenic likely pathogenic

Disease Data

Disease	Source	Batch	Tags	External Links
thyroid cancer	Schubbert et al., 2007, Nat. Rev. Cancer	My Cancer Genome (View variants)	pathogenic	My Cancer Genome
thyroid cancer	Kloos et al., 2009, J. Clin. Oncol.	My Cancer Genome (View variants)	pathogenic	My Cancer Genome
thyroid cancer	Hoftijzer et al., 2009, Eur. J. Endocrinol.	My Cancer Genome (View variants)	pathogenic	My Cancer Genome
thyroid cancer	Ho et al., 2013, N. Engl. J. Med.	My Cancer Genome (View variants)	pathogenic	My Cancer Genome
cancer	MacConaill et al., 2014, J Mol Diagn	Oncomap Variants (View variants)	likely pathogenic

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